Photo-bio-modulation (PBM)
Photobiomodulation (PBM) involves using low-level light, typically red or near-infrared (NIR), to stimulate cellular function. It works by delivering light to tissues, where it’s absorbed by chromophores like cytochrome c oxidase in mitochondria, boosting ATP production, reducing oxidative stress, and modulating inflammation. This can enhance tissue repair and cellular health.
In mental health, PBM is explored for conditions like depression, anxiety, and cognitive decline. It’s applied via devices emitting light to the brain, often through the scalp or intranasally, in a process called transcranial PBM. The light may improve cerebral blood flow, enhance neurogenesis, and regulate neurotransmitter activity, potentially alleviating symptoms. The 1070 nm wavelength falls within this NIR spectrum, allowing it to reach deeper brain tissues.
Uses in Mental Health:
- Depression and Anxiety: Studies suggest PBM may reduce symptoms by modulating brain activity in areas like the prefrontal cortex, improving mood and emotional regulation.
- Cognitive Enhancement: PBM is investigated for boosting memory and attention, particularly in age-related decline or traumatic brain injury.
- Neurodegenerative Disorders: Early research indicates potential benefits in Alzheimer’s and Parkinson’s by reducing neuroinflammation and supporting neuronal survival.
- PTSD and Brain Injury: PBM may aid recovery by reducing inflammation and promoting neural repair.